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Deficiency can lead to a weakened immune response from "summary" of The Vitamin D Solution by Michael F. Holick Ph.D., M.D.

Inadequate levels of vitamin D can compromise the body's ability to fight off infections and diseases. This is because vitamin D plays a critical role in regulating the immune system. When there is a deficiency of vitamin D, the immune system may not function at its optimal level, leaving the body vulnerable to various pathogens. One key way in which vitamin D supports the immune system is by enhancing the function of immune cells. For example, vitamin D helps activate T cells, which are crucial for identifying and destroying harmful invaders in the body. Without sufficient vitamin D, T cells may not be as effective in carrying out their immune def...
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    The Vitamin D Solution

    Michael F. Holick Ph.D., M.D.

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