Deficiency can lead to a weakened immune response from "summary" of The Vitamin D Solution by Michael F. Holick Ph.D., M.D.
Inadequate levels of vitamin D can compromise the body's ability to fight off infections and diseases. This is because vitamin D plays a critical role in regulating the immune system. When there is a deficiency of vitamin D, the immune system may not function at its optimal level, leaving the body vulnerable to various pathogens. One key way in which vitamin D supports the immune system is by enhancing the function of immune cells. For example, vitamin D helps activate T cells, which are crucial for identifying and destroying harmful invaders in the body. Without sufficient vitamin D, T cells may not be as effective in carrying out their immune defense duties. Moreover, vitamin D also helps regulate the production of certain antimicrobial proteins that can directly attack and kill pathogens. In the absence of adequate vitamin D, the production of these antimicrobial proteins may be reduced, making it harder for the body to fend off infections. Another essential role of vitamin D in the immune system is its ability to modulate inflammation. Inflammation is a natural response of the immune system to infections, but excessive or chronic inflammation can be harmful to the body. Vitamin D helps regulate the inflammatory response, ensuring that it is controlled and does not spiral out of control.- A deficiency in vitamin D can weaken the immune response by impairing the function of immune cells, reducing the production of antimicrobial proteins, and disrupting the inflammatory balance. By maintaining optimal levels of vitamin D, individuals can better support their immune system and protect themselves against a wide range of illnesses and infections.
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