Vitamin D deficiency is linked to depression and mood disorders from "summary" of The Vitamin D Solution by Michael F. Holick Ph.D., M.D.
Numerous studies have demonstrated a clear association between low levels of vitamin D and an increased risk of depression and mood disorders. This connection is not surprising when you consider the role that vitamin D plays in the brain. Vitamin D receptors are found throughout the brain, including areas that are involved in the regulation of mood and emotion. When vitamin D levels are low, these receptors may not function optimally, leading to imbalances in neurotransmitters such as serotonin and dopamine that are critical for mood regulation. In addition, vitamin D deficiency has been linked to disruptions in the circadian rhythm, which can contribute to symptoms of depression and other mood disorders. The lack of sunlight exposure that often accompanies low vitamin D levels may further exacerbate these issues by affecting the production of melatonin, a hormone that helps regulate sleep and mood. Furthermore, vitamin D is known to have anti-inflammatory effects, and chronic inflammation has been implicated in the development of depression and other mood disorders. By reducing inflammation in the brain, vitamin D may help protect against the neurobiological changes that underlie these conditions.- The evidence suggests that maintaining adequate levels of vitamin D is essential for supporting mental health and well-being. By addressing vitamin D deficiency through supplementation and lifestyle changes, individuals may be able to reduce their risk of depression and mood disorders and improve their overall quality of life.
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