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Withdrawal symptoms can be severe from "summary" of Drugs, Addiction, and the Brain by George F. Koob,Michael A. Arends,Michel Le Moal

When an individual abruptly stops using a drug to which they have become addicted, they may experience a range of physical and psychological symptoms known as withdrawal. These symptoms can be severe and debilitating, often leading individuals to continue using the drug in order to avoid or alleviate them. The severity of withdrawal symptoms can vary depending on the type of drug used, the duration of use, and the individual's unique physiology. Physical symptoms of drug withdrawal can include nausea, vomiting, sweating, tremors, muscle aches, and headaches. These symptoms can be extremely uncomfortable and may last for several days to weeks, depending on the drug. In some cases, withdrawal symptoms can be life-threatening, such as in the case of severe alcohol or opioid withdrawal, which can result in seizures, delirium, and even death if not properly managed. In addition to physical symptoms, individuals going through drug withdrawal may also experience a range of psychological symptoms, including anxiety, d...
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    Drugs, Addiction, and the Brain

    George F. Koob

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