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Thalassemia diagnosis involves specific laboratory tests from "summary" of Hematology Board Review by Francis P. Worden, MD,Rami N. Khoriaty, MD,Kathleen A. Cooney, MD,Michael W. Deininger, MD, PhD

To diagnose thalassemia, specific laboratory tests must be conducted. These tests are essential to accurately identify the type and severity of thalassemia present in an individual. One of the primary tests used in thalassemia diagnosis is a complete blood count (CBC). This test provides valuable information about the red blood cells, hemoglobin levels, and other blood components. In addition to the CBC, hemoglobin electrophoresis is another crucial test in diagnosing thalassemia. This test separates the different types of hemoglobin present in the blood, allowing healthcare providers to determine if abnormal hemoglobin variants associated with thalassemia are present. Furthermore, genetic testing can be performed to identify specific genetic mutations associated with thalassemia. It is important to note that a thorough medical history and physical examination are also essential components of thalassemia diagnosis. By combining the results of laboratory tests with clinical information, healthcare providers can make an accurate diagnosis and develop an appropriate treatment plan for individuals with thalassemia.
  1. The diagnosis of thalassemia requires a comprehensive approach that includes specific laboratory tests, as well as a thorough evaluation of clinical and genetic information. By using these tools in combination, healthcare providers can effectively diagnose thalassemia and provide appropriate care for individuals affected by this condition.
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Hematology Board Review

Francis P. Worden, MD

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