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The environment can also impact gene expression from "summary" of El gen / The Gene: An Intimate History by Siddhartha Mukherjee

The relationship between genes and the environment is intricate and dynamic. Genes do not operate in isolation; rather, they interact with the environment in complex ways. The environment can have a profound impact on gene expression, shaping how genes are activated or silenced. This concept challenges the notion that genes are solely responsible for determining our traits and behaviors. Instead, it highlights the role of environmental factors in influencing gene activity. The environment can influence gene expression through a variety of mechanisms. For example, environmental factors such as diet, stress, and exposure to toxins can modify the way genes are turned on or off. These modifications can have lasting effects on an individual's health and well-being. Furthermore, the environment can also impact gene expression through epigenetic changes, which involve modifications to the structure of DNA that do not alter the underlying genetic code. Studies have shown that environmental factors can influence gene expression across generations. This phenomenon, known as transgenerational epigenetic inheritance, suggests that the effects of the environment can be passed down from one generation to the next through epigenetic changes. This highlights the interconnectedness of genes and the environment, illustrating how environmental factors can shape not only our own gene expression but also that of future generations. By recognizing the impact of the environment on gene expression, we gain a deeper understanding of the complexity of genetics. Genes are not static entities but are influenced by the dynamic interplay between genetic and environmental factors. This concept underscores the importance of considering both genetic and environmental influences when studying human traits and behaviors. It also emphasizes the need for a holistic approach to understanding the genetic basis of health and disease, taking into account the intricate relationship between genes and the environment.
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    El gen / The Gene: An Intimate History

    Siddhartha Mukherjee

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