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Loss of spatial awareness can lead to bizarre behavior from "summary" of The Man who Mistook His Wife for a Hat by Oliver Sacks

In the world of neurology, the loss of spatial awareness can have profound effects on an individual's behavior. This is exemplified by the case of Dr. P, a music teacher who had difficulty recognizing faces and objects. Dr. P's condition was so severe that he once mistook his own wife for a hat, a bizarre and startling incident that left those around him shocked and confused. Dr. P's inability to perceive spatial relationships correctly led to a series of strange behaviors. For example, he would often become disoriented in familiar places, unable...
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    The Man who Mistook His Wife for a Hat

    Oliver Sacks

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