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Stress can weaken the immune system from "summary" of When the Body Says No by Gabor Maté

In reviewing a vast body of research, scientists have established that the brain and the immune system are in constant communication. Stress, by its very nature, implies a threat to one’s well-being, whether real or perceived. When we feel stressed, the brain sends out signals to the body to prepare for fight or flight. This response is adaptive in the short term, helping us deal with immediate danger. However, prolonged stress can have detrimental effects on the immune system. The stress response involves the release of stress hormones, such as cortisol and adrenaline, which can suppress the immune system. These hormones serve to mobilize the body’s resources for dealing with the perceived threat, diverting energy away from immune function. In the short term, this redirection of resources is not problematic. However, chronic stress can lead to a state of prolonged immune suppression, leaving the body vulnerable to infections and diseases. Moreover, stress can also impact the production of white blood cells, which play a crucial role in fighting off pathogens. Research has shown that chronic stress can reduce the number of white blood cells circulating in the body, making it harder for the immune system to mount an effective response to threats. In this way, stress can weaken the body’s defenses and make it more susceptible to illness. Furthermore, chronic stress can contribute to the development of inflammatory conditions, such as autoimmune diseases. Inflammation is a natural response of the immune system to injury or infection. However, when inflammation becomes chronic, it can damage healthy tissues and organs. Stress has been shown to contribute to the dysregulation of the immune system, leading to persistent inflammation and increased risk of autoimmune disorders.
  1. The connection between stress and the immune system is a complex and multifaceted one. While the stress response is a natural and adaptive mechanism, chronic stress can have profound effects on immune function. By understanding the impact of stress on the immune system, we can begin to take steps to mitigate its detrimental effects and promote overall well-being.
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When the Body Says No

Gabor Maté

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