Chronic stress can contribute to autoimmune disorders from "summary" of When the Body Says No by Gabor Maté
When we are faced with chronic stress, our bodies experience a constant state of heightened arousal. This prolonged activation of our stress response systems can have a profound impact on our immune function. The immune system is finely tuned to respond to threats from the outside world, such as viruses and bacteria. However, when the body is chronically stressed, this delicate balance can be disrupted. The stress hormones that are released during periods of prolonged stress can suppress the immune system's ability to mount an effective response to foreign invaders. This can leave the body more vulnerable to infections and other health challenges. In addition, chronic stress can also lead to inflammation in the body. Inflammation is a normal part of the immune response, but when it becomes chronic, it can contribute to the development of autoimmune disorders. Autoimmune disorders occur when the immune system mistakenly attacks the body's own tissues. This can result in a range of symptoms and health problems, depending on which tissues are targeted. The connection between chronic stress and autoimmune disorders lies in the dysregulation of the immune system that occurs when the body is under prolonged stress. The constant activation of the stress response can disrupt the immune system's ability to distinguish between self and non-self, leading to an autoimmune response. In addition to the direct effects of stress on the immune system, chronic stress can also contribute to autoimmune disorders through its impact on other systems in the body. For example, stress can disrupt the balance of gut bacteria, leading to increased intestinal permeability. This can allow bacteria and other substances to leak into the bloodstream, triggering an immune response and potentially contributing to the development of autoimmune disorders.- The link between chronic stress and autoimmune disorders is complex and multifaceted. By understanding the ways in which stress can impact the immune system and contribute to dysregulation, we can begin to appreciate the importance of managing stress for overall health and well-being.
