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Epidemics and diseases ravaged the population from "summary" of The Decline and Fall of the Roman Empire by Edward Gibbon

The Roman Empire faced a period of great turmoil as epidemics and diseases swept through the population. The once-mighty empire found itself unable to combat the devastating effects of these afflictions, which ravaged both the rich and the poor with equal ferocity. The outbreaks of disease were not confined to any one region or social class, but spread rapidly throughout the empire, leaving death and destruction in their wake. The lack of effective medical knowledge and infrastructure only served to exacerbate the situation, as physicians were unable to provide adequate treatment to those who fell ill. The impact of these epidemics on the population was profound, as entire communities were decimated and social structures were thrown...
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    The Decline and Fall of the Roman Empire

    Edward Gibbon

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