Recognizing transfusion reactions is crucial for patient safety from "summary" of Hematology Board Review by Francis P. Worden, MD,Rami N. Khoriaty, MD,Kathleen A. Cooney, MD,Michael W. Deininger, MD, PhD
The recognition of transfusion reactions is essential for ensuring the safety of patients undergoing blood transfusions. These reactions can vary in severity, from mild to life-threatening, and can present with a wide range of symptoms. It is crucial for healthcare providers to be able to identify these reactions promptly and take appropriate action to prevent any harm to the patient. Transfusion reactions can be classified into two main categories: immune-mediated reactions and non-immune reactions. Immune-mediated reactions are caused by the recipient's immune system reacting to antigens present in the transfused blood. These reactions can manifest as hemolytic reactions, febrile non-hemolytic reactions, allergic reactions, or transfusion-related acute lung injury (TRALI). Non-immune reactions, on the other hand, are not caused by an immune response and can include transfusion-associated circulatory overload (TACO), sepsis, and iron overl...
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