Pharmacophore identification in drug discovery from "summary" of Chemistry for Pharmacy Students by Lutfun Nahar,Professor Satyajit D. Sarker
Pharmacophore identification is a crucial step in the process of drug discovery. It involves the identification of the key structural and chemical features of a molecule that are necessary for its biological activity. By understanding the pharmacophore of a drug, researchers can design new compounds that are more potent, selective, and safe. The pharmacophore of a drug is typically defined by a set of functional groups and their relative positions in three-dimensional space. These functional groups interact with specific binding sites on target proteins, leading to the desired pharmacological effect. Identifying the pharmacoph...
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