Bioavailability and bioequivalence from "summary" of Chemistry for Pharmacy Students by Lutfun Nahar,Professor Satyajit D. Sarker
Bioavailability is a crucial concept in pharmacokinetics as it refers to the fraction of an administered dose of a drug that reaches the systemic circulation in an unchanged form. This is an important parameter to consider when evaluating the effectiveness of a drug as it determines the amount of drug available for therapeutic action. Bioavailability is influenced by various factors such as the route of administration, drug formulation, metabolism, and excretion. Bioequivalence, on the other hand, is a term used to compare the bioavailability of different formulations of the same drug. It is essential to ensure that generic formulations of a drug are bioequivalent to the original branded product. This is because bioequivalence indicates that the generic drug will produce the same therapeu...
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