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How genes are expressed from "summary" of Biology by Neil A. Campbell

Genes are the units of heredity, containing specific instructions for making proteins. The process by which these instructions are used to produce a functional product is called gene expression. Gene expression involves two main stages: transcription and translation. Transcription is the first step in gene expression, where a segment of DNA is copied into a messenger RNA (mRNA) molecule by an enzyme called RNA polymerase. This mRNA molecule carries the genetic information from the nucleus to the cytoplasm, where protein synthesis takes place. During transcription, only one of the two DNA strands, known as the template strand, is used as a template to synthesize the mRNA molecule. Translation is the second stage of gene expression, where the information carried by the mRNA molecule is used to assemble a specific sequence of amino acids into a protein. This process occurs in the ribosomes, which are the cellular structures responsible for protein synthesis. Transfer RNA (tRNA) molecules bring the appropriate amino acids to the ribosome, based on the codons (three-nucleotide sequences) on the mRNA molecule. The genetic code is the set of rules that specifies the relationship between the sequence of nucleotides in the mRNA molecule and the sequence of amino acids in the resulting protein. Each set of three nucleotides on the mRNA molecule, known as a codon, codes for a specific amino acid. There are 64 possible codons, but only 20 amino acids, so some amino acids are specified by more than one codon. Gene expression is a tightly regulated process, with multiple levels of control to ensure that genes are expressed at the right time and in the right amount. Regulatory proteins can bind to specific DNA sequences near genes and either enhance or inhibit transcription. Additionally, epigenetic modifications, such as DNA methylation and histone modification, can influence gene expression by altering the accessibility of genes to transcription factors. Understanding how genes are expressed is essential for comprehending the molecular basis of genetics and how genetic information is used to create the diverse array of proteins that carry out the functions of living organisms. Gene expression is a complex and highly regulated process that plays a crucial role in determining the characteristics of an organism.
    oter

    Biology

    Neil A. Campbell

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