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Sleep is necessary for the brain to clear waste and toxins from "summary" of Why We Sleep by Matthew Walker

In order for the brain to function optimally, it must have the opportunity to clear away waste and toxins that accumulate throughout the day. Sleep provides the necessary time and conditions for this crucial process to occur. Without sufficient sleep, these waste products can build up and impair the brain's ability to function effectively. One of the key waste-clearing mechanisms that takes place during sleep is the glymphatic system. This system, discovered relatively recently by scientists, works to flush out toxins and other harmful substances that can interfere with the brain's normal functioning. During sleep, the glymphatic system is particularly active, helping to cleanse the brain of waste materials that have accumulated during waking hours. Inadequate sleep can disrupt...
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    Why We Sleep

    Matthew Walker

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